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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPEF2
All Species:
8.79
Human Site:
S419
Identified Species:
17.58
UniProt:
O14830
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14830
NP_006230.2
753
86518
S419
E
K
E
E
P
S
R
S
A
S
E
A
D
S
E
Chimpanzee
Pan troglodytes
XP_526584
753
86517
S419
E
K
E
E
P
F
R
S
A
S
E
A
D
S
E
Rhesus Macaque
Macaca mulatta
XP_001100042
753
86580
S419
Q
K
E
E
P
S
R
S
A
S
E
A
D
S
E
Dog
Lupus familis
XP_544934
970
109306
L620
G
G
G
E
P
P
A
L
H
A
R
S
R
L
G
Cat
Felis silvestris
Mouse
Mus musculus
O35385
757
86627
P423
G
E
S
L
P
L
A
P
D
A
D
C
V
A
D
Rat
Rattus norvegicus
Q3SWT6
640
73948
E319
P
P
M
S
T
N
Q
E
C
N
I
K
K
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510316
925
101565
K507
D
E
F
E
H
A
W
K
L
F
G
S
H
M
N
Chicken
Gallus gallus
XP_420595
713
82896
D392
E
W
C
R
K
L
V
D
I
S
D
S
E
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108202
718
82122
D397
R
P
P
P
S
P
T
D
M
L
Q
V
P
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40421
661
75493
G340
R
G
A
G
V
W
F
G
P
D
V
T
D
N
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780182
694
79630
L373
P
D
V
T
K
K
V
L
A
K
H
G
I
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Conservation
Percent
Protein Identity:
100
99.1
95.4
55
N.A.
82.6
43
N.A.
26
66.2
N.A.
52.5
N.A.
29.3
N.A.
N.A.
36.2
Protein Similarity:
100
99.8
97.7
62.4
N.A.
90.8
61.6
N.A.
37.7
77.5
N.A.
66.2
N.A.
46.3
N.A.
N.A.
52.9
P-Site Identity:
100
93.3
93.3
13.3
N.A.
6.6
0
N.A.
6.6
20
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
100
26.6
N.A.
40
33.3
N.A.
33.3
40
N.A.
6.6
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
17
0
34
17
0
25
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
9
0
0
9
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
17
9
9
17
0
34
9
9
% D
% Glu:
25
17
25
42
0
0
0
9
0
0
25
0
9
9
34
% E
% Phe:
0
0
9
0
0
9
9
0
0
9
0
0
0
9
9
% F
% Gly:
17
17
9
9
0
0
0
9
0
0
9
9
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
9
0
9
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
9
0
9
0
0
% I
% Lys:
0
25
0
0
17
9
0
9
0
9
0
9
9
0
9
% K
% Leu:
0
0
0
9
0
17
0
17
9
9
0
0
0
9
17
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
9
0
0
0
17
9
% N
% Pro:
17
17
9
9
42
17
0
9
9
0
0
0
9
0
0
% P
% Gln:
9
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
17
0
0
9
0
0
25
0
0
0
9
0
9
0
0
% R
% Ser:
0
0
9
9
9
17
0
25
0
34
0
25
0
25
0
% S
% Thr:
0
0
0
9
9
0
9
0
0
0
0
9
0
0
0
% T
% Val:
0
0
9
0
9
0
17
0
0
0
9
9
9
0
0
% V
% Trp:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _